Introduction. Nasolabial folds are skin folds that run from both sides of the nose to the corners of the mouth. They are caused by the loss of fat in the dermis, followed by the loss of muscles in the middle part of the face.
Aim. The aim of the work is to present contemporary knowledge of materials used for modeling nasolabial folds.
Material and Methods. Medical databases PubMed, EBSCO Multiplier, were analyzed by entering the slogans: nasolabial folds, nasolabial folds, hyaluronic acid in nasolabial fold modeling, nasolabial fold correction. Analyzing the literature, data from eleven scientific articles from the last five years (2013–2018) were used.
Results. In most articles for modeling nasolabial folds, crosslinked hyaluronic acid was used after prior photographic assessment of skin condition or after anamnesis examination — an interview. From the papers describing the cases, it appears that the applied materials for face aesthetic medicine treatments level the nasolabial folds.
Conclusions. The obtained results are ambiguous and studies need to be continued. In the literature, the instrumental evaluation of facial skin was not used before modeling nasolabial folds.
Adamson PA, Doud Gail SK. Modern concepts of beauty. Last Surg Nuts. 2009;29(1):5–9.
De Melo F, Nicolau P, Piovano L, Lin SL, Baptista‑Fernandes T, King MI, Camporese A, Hong KK, Khattar MM, Christen MO. Recommendations for volume augmentation and rejuvenation of the face and hands with the new generation polycaprolactone‑based collagen stimulator (Ellansé®). Clinical Cosmetic and Investigational Dermatology. 2017;10:431–440.
Robati RM, Abdollahimajd F, Robati AM. Evaluation of Subcision for the Correction of the Prominent Nasolabial Folds. Dermatology Research and Practice. 2015;1–7. Doi: 10.1155/2015/976153.
Chilicka K, Koznarska A, Wesołowska L. The influence of hyaluronic acid‑based no‑needle mesotherapy on skin hydration in anti‑aging prevention. A preliminary report. Higher School's Pulse. 2016;10(3):17–20.
Oni G, Hoxworth R, Teotia S, Brown S, Kenkel JM. Evaluation of a Microfocused Ultrasound System for Improving Skin Laxity and Tightening in the Lower Face. Aesthetic Surgery Journal. 2014;34(7):1099–1110.
Gutowski KA. Hyaluronic Acid Fillers. Clinics in Plastic Surgery. 2016;43(3):489–496.
Chang CS, Kang GC. Achieving Ideal Lower Face Aesthetic Contours: Combination of Tridimensional Fat Grafting to the Chin with Masseter Botulinum Toxin Injection. Aesthetic Surgery Journal. 2016;36(10): 1093–1100.
Modrzyński M, Ignaciuk A. The minimally invasive rhinoplasty with hyaluronic acid and botulinum toxin in a 49-year old woman. Otolaryngologia Polska. 2010;64(5):324–327.
Philipp‑Dormston WG, Wong C, Schuster B, Larsson MK, Podda M. Evaluating Perceived Naturalness of Facial Expression After Fillers to the Nasolabial Folds and Lower Face With Standardized Video and Photography. Dermatologic Surgery. 2018;44(6):826–832.
Nowacki M, Pietkun K, Pokrywczyńska M, Rasmus M, Warda K, Kloskowski T, Jundziłł A, Gagat M, Grzanka A, Bondar M, Marszałek A, Drewa T, Czajkowski R. Filling Effects, Persistence, and Safety of Dermal Fillers Formulated With Stem Cells in an Animal Model. Aesthetic Surgery Journal. 2014;34(8):1261–1269.
Sevilla GP, Dhurat RS, Shetty G, Kadam PP, Totey SM. Safety and Efficacy of Growth Factor Concentrate in the Treatment of Nasolabial Fold Correction: Split Face Pilot Study. Indian J Dermatol. 2015;60(5):520.
Centeno RF. Combination volume rejuvenation therapy of the face: fat, fillers, and Botox. Aesthet Surg J. 2006;26(4):460–464.
Baspeyras M, Dallara JM, Cartier H, Charavel MH, Dumas L. Restoring jawline contour with calcium hydroxylapatite: A prospective, observational study. J Cosmet Dermatol. 2017;16(3):342–347.
Cohen S, Dover J, Monheit G, Narins R, Sadick N, Werschler WP, Karnik J, Smith SR. Five‑Year Safety and Satisfaction Study of PMMA‑Collagen in the Correction of Nasolabial Folds. Dermatol Surg. 2015;41(1):302–313.
Wu Y, Sun N, Xu Y, Liu H, Zhong S, Chen L, Li D. Clinical comparison between two hyaluronic acid derived fillers in the treatment of nasolabial folds in Chinese subjects: BioHyalux versus Restylane. Arch Dermatol Res. 2016;308(3):145–151.
Nisi G, Cuomo R, Brandi C, Grimaldi L, Sisti A, D’Aniello C. Carbon dioxide therapy and hyaluronic acid for cosmetic correction of the nasolabial folds. Journal of Cosmetic Dermatology. 2016,15(2):169–175.
Zhou SB, Xie Y, Chiang CA, Liu K, Li QF; A Randomized Clinical Trial of Comparing Monophasic Monodensified and Biphasic Nonanimal Stabilized Hyaluronic Acid Dermal Fillers in Treatment of Asian Nasolabial Folds. Dermatologic Surgery. 2016;42(9):1061–1068.
Downie JB, Grimes PE, Callender VD. A Multicenter Study of the Safety and Effectiveness of Hyaluronic Acid with a Cohesive Polydensified Matrix for Treatment of Nasolabial Folds in Subjects with Fitzpatrick Skin Types IV, V, and VI. Plastic and Reconstructive Surgery. 2013;132(4/2):41–47.
Baumann L, Weiss RA, Grekin S, Narins R, Gold M, Donofrio L, Nogueira A, Shawcross H, Brown S, Mashburn JH. Comparison of Hyaluronic Acid Gel With (HARDL) and Without Lidocaine (HAJUP) in the Treatment of Moderate‑To‑Severe Nasolabial Folds: A Randomized, Evaluator‑Blinded Study. Dermatologic Surgery. 2018;44(6):833–840.
Lee YB, Song EJ, Kim SS, Kim JW, Yu DS. Safety and efficacy of a novel injectable filler in the treatment of nasolabial folds: Polymethylmethacrylate and cross‑linked dextran in hydroxypropyl methylcellulose. Journal of Cosmetic and Laser Therapy. 2014;16(4):185–190.
Beer KR. Safety and effectiveness of injection of calcium hydroxylapatite via blunt cannula compared to injection by needle for correction of nasolabial folds. Journal of Cosmetic Dermatology. 2014;13(4):288–296.
Choi WJ, Han SW, Kim JE, Kim HW, Kim MB, Kang H. The Efficacy and Safety of Lidocaine‑Containing Hyaluronic Acid Dermal Filler for Treatment of Nasolabial Folds: A Multicenter Randomized Clinical Study. Aesthetic Plastic Surgery. 2015;39(6):953–962.
Monheit G, Beer K, Hardas B, Grimes PE, Weichman BM, Lin V,Murphy DK. Safety and Effectiveness of the Hyaluronic Acid Dermal Filler VYC-17.5L for Nasolabial Folds: Results of a Randomized, Controlled Study. Dermatol Surg. 2018;44(5):670–678.
Lee JH, Choi YS, Kim SM, Kim YJ, Rhie JW, Jun YJ. Efficacy and Safety of Porcine Collagen Filler for Nasolabial Fold Correction in Asians: A Prospective Multicenter, 12 Months Follow‑up Study. J Korean Med Sci. 2014; 29(3):217–221.
Suh JH, Oh CT, Im SI, Lim JS, Kim BJ, Lee JH. A multicenter, randomized, double‑blind clinical study to evaluate the efficacy and safety of a new monophasic hyaluronic acid filler with lidocaine 0.3% in the correction of nasolabial fold. J Cosmet Dermatol. 2017;16(3):327–332.
D’Aloiso MC, Senzolo M, Azzena B. Efficacy and Safety of Cross‑Linked Carboxymethylcellulose Filler for Rejuvenation of the Lower Face: A 6-Month Prospective Open‑Label Study. Dermatol Surg. 2016;42(2):209–217.
Dallara JM, Baspeyras M, Bui P, Cartier H, Charavel MH, Dumas L. Calcium hydroxylapatite for jawline rejuvenation: consensus recommendations. J Cosmet Dermatol. 2014;13(1):3–14.
Matthews‑Brzozowska T, Łącka M, Kawałkiewicz W, Mojs E, Kubisz L. Minimally invasive treatments revitalizing facial skin — a case study. Journal of Medical Science. 2018; 87(1): 48–54.
Vedamurthy M. Beware What You Inject: Complications of Injectables‑Dermal Fillers. J Cutan Aesthet Surg. 2018;11(2):60–66.